This paper presents a detailed safety review of noni (Morinda citrifolia) fruit juice, focusing on its chemical composition, history of use, toxicological studies, and reported adverse events. It emphasizes that noni juice has a long history of traditional use and has been consumed safely by large populations worldwide. The juice contains numerous beneficial compounds, such as polyphenols, flavonoids, and iridoids, which have demonstrated antioxidant and anti-inflammatory properties. Toxicology studies in animals and humans showed no significant toxicity, even at relatively high doses. Additionally, the paper references regulatory approvals, including the European Food Safety Authority’s (EFSA) positive opinions and the FDA’s GRAS (Generally Recognized as Safe) notifications for noni juice.
The review also addresses concerns about liver toxicity, referencing a few case reports where individuals developed liver-related issues allegedly linked to noni juice consumption. However, upon closer examination, these cases often involved confounding factors such as preexisting conditions or use of other substances. The authors argue that the available evidence does not establish a causal relationship between noni juice and liver damage. In conclusion, the paper affirms that noni juice is safe for general consumption within recommended doses and underlines the importance of considering the totality of evidence when evaluating isolated adverse reports.
JOURNAL OF FOOD SCIENCE—Vol. 71, Nr. 8, 2006, www.ift.org
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