A recent study from Airlangga University in Indonesia investigated the antibacterial effects of methanol extract from *Morinda citrifolia* (noni) fruit against *Staphylococcus aureus* and methicillin-resistant *Staphylococcus aureus* (MRSA). Using the well-diffusion method, researchers found that noni fruit extract exhibited significant antibacterial activity against both bacteria, with the strongest effect observed at 100% concentration. Notably, the noni extract had even greater effectiveness than standard antibiotics: it outperformed erythromycin against *S. aureus* and vancomycin against MRSA. The minimum bactericidal concentration (MBC) was determined to be 6.25% for *S. aureus* and 3.13% for MRSA.
The study attributes noni’s antibacterial power to its rich array of bioactive compounds, including quercetin, vitamin C, coumarins, and lignans. These phytochemicals work by disrupting bacterial cell membranes, inhibiting energy production, and interfering with DNA replication—particularly effective strategies against drug-resistant bacteria like MRSA. While the use of methanol as an extraction solvent may contribute slightly to the observed antibacterial effects, the study confirms that the active compounds within noni are primarily responsible. These results support further exploration of noni fruit as a natural topical or oral antibacterial agent, especially in light of rising antibiotic resistance worldwide.
*Published in the International Journal of Research Publications, 2022. [www.ijrp.org](https://www.ijrp.org)*
**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.**